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Naif O Al-Harbi Selected Research

1-methyl-1H-indole-2-carboxylic acid (4- (1- (4- (4- acetylpiperazin- 1- yl)cyclohexyl)- 4- amino- 1H- pyrazolo(3,4- d)pyrimidin- 3- yl)- 2- methoxyphenyl)amide

1/2022Lck signaling inhibition causes improvement in clinical features of psoriatic inflammation through reduction in inflammatory cytokines in CD4+ T cells in imiquimod mouse model.

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Naif O Al-Harbi Research Topics

Disease

38Inflammation (Inflammations)
06/2022 - 08/2014
12Autistic Disorder (Autism)
05/2022 - 03/2017
11Psoriasis (Pustulosis Palmaris et Plantaris)
06/2020 - 09/2015
9Asthma (Bronchial Asthma)
10/2019 - 05/2015
8Cardiotoxicity
04/2020 - 09/2014
7Acute Lung Injury
06/2022 - 12/2015
5Multiple Myeloma
08/2019 - 01/2016
4Acute Kidney Injury (Acute Renal Failure)
10/2021 - 05/2018
3Sepsis (Septicemia)
01/2021 - 05/2018
2Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
06/2022 - 06/2021
2Neoplasms (Cancer)
04/2022 - 01/2019
2Otitis
01/2022 - 01/2017
2Wounds and Injuries (Trauma)
08/2020 - 01/2014
2Pneumonia (Pneumonitis)
01/2019 - 11/2018
2Lung Injury
12/2015 - 01/2015
1Autism Spectrum Disorder
01/2022
1Hypertension (High Blood Pressure)
01/2021
1Cardiomegaly (Heart Hypertrophy)
01/2021
1Genetic Predisposition to Disease (Genetic Predisposition)
01/2021
1Kidney Neoplasms (Kidney Cancer)
08/2020
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2020
1Tuberculosis (Tuberculoses)
03/2020
1Drug-Related Side Effects and Adverse Reactions
03/2020

Drug/Important Bio-Agent (IBA)

16AntioxidantsIBA
04/2022 - 12/2013
16CytokinesIBA
01/2022 - 06/2015
12Imiquimod (Aldara)FDA LinkGeneric
01/2022 - 09/2015
11Interleukin-17 (Interleukin 17)IBA
01/2022 - 05/2016
11Peroxidase (Myeloperoxidase)IBA
06/2020 - 09/2015
93-nitrotyrosineIBA
10/2021 - 04/2016
9Oxidants (Oxidizing Agents)IBA
02/2021 - 08/2014
8NADPH Oxidases (NAD(P)H oxidase)IBA
02/2021 - 04/2016
8Lipid PeroxidesIBA
02/2021 - 05/2015
6Pharmaceutical PreparationsIBA
08/2020 - 08/2014
6Biomarkers (Surrogate Marker)IBA
07/2019 - 12/2013
6Proteins (Proteins, Gene)FDA Link
01/2018 - 12/2013
5apremilastIBA
06/2022 - 11/2016
5Transcription Factors (Transcription Factor)IBA
10/2021 - 09/2015
5EnzymesIBA
02/2021 - 12/2013
5AllergensIBA
10/2019 - 04/2016
5carfilzomibIBA
08/2019 - 01/2016
4phthalic acid (phthalate)IBA
05/2022 - 12/2020
4Phosphotransferases (Kinase)IBA
01/2022 - 10/2019
4CreatinineIBA
10/2021 - 05/2017
4Diethylhexyl Phthalate (DEHP)IBA
02/2021 - 01/2018
4Proteasome InhibitorsIBA
08/2019 - 11/2016
4Interleukin-6 (Interleukin 6)IBA
01/2019 - 06/2015
3Doxorubicin (Adriamycin)FDA LinkGeneric
04/2022 - 10/2018
3Agammaglobulinaemia Tyrosine KinaseIBA
01/2021 - 10/2019
3PlasticizersIBA
01/2021 - 01/2018
3ibrutinibIBA
06/2020 - 10/2019
3Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
06/2020 - 04/2016
3Dexamethasone (Maxidex)FDA LinkGeneric
10/2019 - 05/2016
3Adrenal Cortex Hormones (Corticosteroids)IBA
10/2019 - 01/2018
3Rutin (Rutoside)IBA
08/2019 - 01/2014
3Urea (Carbamide)FDA LinkGeneric
03/2019 - 05/2017
3NitrogenIBA
03/2019 - 05/2017
3Syk KinaseIBA
03/2019 - 03/2019
3Carbon Tetrachloride (Tetrachloromethane)IBA
01/2017 - 01/2014
2Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2022 - 10/2019
2Interleukin-10 (Interleukin 10)IBA
10/2021 - 06/2020
2Environmental Pollutants (Pollutants, Environmental)IBA
02/2021 - 01/2021
2Messenger RNA (mRNA)IBA
01/2021 - 01/2016
2Carnitine (L-Carnitine)FDA LinkGeneric
01/2021 - 01/2012
2Toll-Like Receptor 4IBA
07/2020 - 03/2017
2sulforaphaneIBA
07/2019 - 01/2019
2LipidsIBA
07/2019 - 01/2017
2Glutathione Transferase (Glutathione S-Transferase)IBA
07/2019 - 01/2015
2ChemokinesIBA
05/2019 - 11/2018
2Acetates (Acetic Acid Esters)FDA Link
05/2018 - 01/2017
2Interleukin-17 ReceptorsIBA
01/2018 - 01/2017
2Aspartate Aminotransferases (Aspartate Transaminase)IBA
01/2017 - 12/2014
2LipopolysaccharidesIBA
05/2016 - 01/2015
2Renin InhibitorsIBA
12/2015 - 12/2014
2Immunosuppressive Agents (Immunosuppressants)IBA
12/2015 - 12/2014
2aliskirenFDA Link
12/2015 - 12/2014
2Tacrolimus (Prograf)FDA LinkGeneric
12/2015 - 12/2014
2IfosfamideFDA LinkGeneric
09/2014 - 01/2012
1AcidsIBA
06/2022
1geraniol (nerol)IBA
04/2022
1p38 Mitogen-Activated Protein KinasesIBA
01/2022
11-methyl-1H-indole-2-carboxylic acid (4- (1- (4- (4- acetylpiperazin- 1- yl)cyclohexyl)- 4- amino- 1H- pyrazolo(3,4- d)pyrimidin- 3- yl)- 2- methoxyphenyl)amideIBA
01/2022
1statticIBA
06/2021
1DNA (Deoxyribonucleic Acid)IBA
01/2021
1Acetylcarnitine (Alcar)IBA
01/2021
1Myosin Heavy Chains (Myosin Heavy Chain)IBA
01/2021
1Insulin (Novolin)FDA Link
01/2021
1RivaroxabanIBA
08/2020
1Sunitinib (Sutent)FDA Link
08/2020
1Glutathione PeroxidaseIBA
06/2020
1Superoxide DismutaseIBA
06/2020
1Glutathione Reductase (Glutathione-Disulfide Reductase)IBA
06/2020
1Cadherins (E-Cadherin)IBA
06/2020
1LiraglutideFDA Link
04/2020
1Gefitinib (Iressa)FDA Link
04/2020
1Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
01/2020
1Basic-Leucine Zipper Transcription FactorsIBA
01/2020
1emt protein-tyrosine kinase (IL2-inducible T-cell kinase)IBA
10/2019
1Interleukin-2 (IL2)IBA
10/2019
1RoflumilastIBA
07/2019

Therapy/Procedure

10Therapeutics
03/2020 - 01/2012